Linda P Dwoskin Selected Research

1- (3- picolinium)- 12- triethylammonium- dodecane dibromide

10/2007

Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD).

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Linda P Dwoskin Research Topics

Disease

17	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 12/2018 - 11/2006
13	Tobacco Use Disorder (Nicotine Dependence) 12/2018 - 03/2007
8	Substance-Related Disorders (Drug Abuse) 01/2019 - 11/2006
5	Cocaine-Related Disorders (Cocaine Addiction) 12/2016 - 03/2011
3	Obesity 01/2020 - 11/2006
2	Cardiotoxicity 11/2019 - 01/2018
2	Neoplasms (Cancer) 01/2019 - 01/2016
2	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 01/2016
2	Hypertension (High Blood Pressure) 09/2013 - 07/2013
2	Pain (Aches) 11/2011 - 04/2011
1	Weight Gain 01/2020
1	Hemolysis 02/2019
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2019
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2019
1	Nausea 12/2018
1	Colorectal Neoplasms (Colorectal Cancer) 07/2014
1	Pathologic Processes 07/2013
1	Alcoholism (Alcohol Abuse) 07/2013
1	Mood Disorders (Mood Disorder) 07/2013
1	Cognitive Dysfunction 07/2013
1	Neuralgia (Stump Neuralgia) 11/2011
1	Chronic Pain 11/2011
1	Hyperalgesia 11/2011
1	Acquired Immunodeficiency Syndrome (AIDS) 12/2009
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 11/2006
1	Huntington Disease (Huntington's Disease) 04/2002

Drug/Important Bio-Agent (IBA)

13	Methylphenidate (Ritalin)FDA LinkGeneric 12/2018 - 03/2011
13	Nicotine FDA Link 11/2017 - 11/2006
7	Dopamine (Intropin)FDA LinkGeneric 11/2017 - 07/2013
7	Cocaine (Cocaine HCl)IBA 10/2017 - 07/2013
7	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2016 - 10/2007
4	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 07/2013 - 03/2011
3	Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric 07/2014 - 05/2013
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 12/2013 - 07/2013
2	Bupropion (Wellbutrin)FDA LinkGeneric 01/2017 - 11/2006
2	Proteins (Proteins, Gene)FDA Link 01/2017 - 01/2016
2	Dextroamphetamine (Dexedrine)FDA LinkGeneric 12/2016 - 01/2016
2	Analgesics (Analgesic Drugs)IBA 11/2011 - 04/2011
2	Pharmaceutical PreparationsIBA 03/2011 - 04/2007
2	Biological ProductsIBA 03/2011 - 01/2011
2	nornicotineIBA 04/2007 - 03/2007
1	SaccharinIBA 01/2020
1	Sucrose (Saccharose)IBA 01/2020
1	Ether (Diethyl Ether)IBA 11/2019
1	N- (1,2- dihydroxylpropyl)- 2,6- di- (4- methoxyphenethyl)piperidineIBA 11/2019
1	Antifungal AgentsIBA 02/2019
1	Voriconazole (Vfend)FDA LinkGeneric 02/2019
1	Cholinergic Agents (Cholinergics)IBA 01/2019
1	LigandsIBA 01/2019
1	auroneIBA 01/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	TubulinIBA 01/2019
1	Colchicine FDA LinkGeneric 01/2019
1	Lobeline (Smokeless)IBA 12/2018
1	Methamphetamine (Desoxyn)FDA LinkGeneric 01/2018
1	anatabineIBA 11/2017
1	myosmineIBA 11/2017
1	Topiramate (Topamax)FDA LinkGeneric 01/2017
1	Naltrexone (ReVia)FDA LinkGeneric 01/2017
1	Phentermine (Adipex-P)FDA LinkGeneric 01/2017
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2016
1	prostate apoptosis response-4 proteinIBA 01/2016
1	VimentinIBA 01/2016
1	glucose receptorIBA 01/2016
1	AlkaloidsIBA 01/2016
1	Serotonin (5 Hydroxytryptamine)IBA 10/2015
1	Conotoxins (Conotoxin)IBA 10/2015
1	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 08/2015
1	Glutamic Acid (Glutamate)FDA Link 03/2015
1	Methionine (L-Methionine)FDA Link 07/2014
1	EnzymesIBA 07/2014
1	Dopamine D1 Receptors (Dopamine D1 Receptor)IBA 07/2014
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 09/2013
1	AngiotensinsIBA 09/2013
1	Antihypertensive Agents (Antihypertensives)IBA 07/2013
1	MecamylamineIBA 07/2013
1	Therapeutic UsesIBA 07/2013
1	Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA 02/2013
1	Formaldehyde (Formol)FDA Link 11/2011
1	5,5',5',5'- (1,2,4,5- benzenetetrayl)tetrakis- (1- (3- phenylpyridinium)- 4- pentyne)IBA 11/2011
1	Peptides (Polypeptides)IBA 04/2011
1	1- (3- picolinium)- 12- triethylammonium- dodecane dibromideIBA 10/2007
1	3-nitropropionic acidIBA 04/2002
1	malonic acid (malonate)IBA 04/2002

Therapy/Procedure

9	Self Administration (Administration, Self) 10/2017 - 03/2007
7	Drug Therapy (Chemotherapy) 12/2018 - 03/2007
5	Therapeutics 01/2019 - 03/2007
1	Oral Administration 01/2018
1	Aftercare (After-Treatment) 08/2015